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A review of orthostatic blood pressure regulation and its association with mood and cognition.
Perlmuter, Lawrence C; Sarda, Garima; Casavant, Vanessa; O'Hara, Kimberly; Hindes, Mariah; Knott, Patrick T; Mosnaim, Aron D.
Afiliación
  • Perlmuter LC; Department of Psychology, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Rd, North Chicago, IL 60064, USA. lawrence.perlmuter@rosalindfranklin.edu
Clin Auton Res ; 22(2): 99-107, 2012 Apr.
Article en En | MEDLINE | ID: mdl-21948454
AIMS: This paper will review literature that examines the psychological and neuropsychological correlates of orthostatic blood pressure regulation. RESULTS: The pattern of change in systolic blood pressure in response to the shift from supine to upright posture reflects the adequacy of orthostatic regulation. Orthostatic integrity involves the skeletal muscle pump, neurovascular compensation, neurohumoral effects and cerebral flow regulation. Various physiological states and disease conditions may disrupt these mechanisms. Clinical and subclinical orthostatic hypotension has been associated with impaired cognitive function, decreased effort, reduced motivation and increased hopelessness as well as dementia, diabetes mellitus, and Parkinson's disease. Furthermore, inadequate blood pressure regulation in response to orthostasis has been linked to increased depression and anxiety as well as to intergenerational behavioral sequalae. CONCLUSIONS: Identifying possible causes and consequences of subclinical and clinical OH are critical in improving quality of life for both children and older adults.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Shy-Drager / Presión Sanguínea / Circulación Cerebrovascular / Trastornos del Conocimiento / Trastornos del Humor Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Animals / Humans Idioma: En Revista: Clin Auton Res Asunto de la revista: NEUROLOGIA Año: 2012 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Shy-Drager / Presión Sanguínea / Circulación Cerebrovascular / Trastornos del Conocimiento / Trastornos del Humor Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Animals / Humans Idioma: En Revista: Clin Auton Res Asunto de la revista: NEUROLOGIA Año: 2012 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania