[Update on the treatment of endemic hemolytic uremic syndrome. Pathogenesis and treatment of the most severe systemic complication of infections by Shiga toxin-producing Escherichia coli]. / Actualización en el tratamiento del síndrome urémico hemolítico endémico. Patogénesis y tratamiento de la complicación sistémica más grave de las infecciones por Escherichia coli productor de toxina Shiga.
Medicina (B Aires)
; 71(4): 383-9, 2011.
Article
en Es
| MEDLINE
| ID: mdl-21893458
The typical form of hemolytic uremic syndrome (HUS) is the major complication of Shiga toxin-producing Escherichia coli (STEC) infections. HUS is a critical health problem in Argentina since it is the main cause of acute renal failure in children and the second cause of chronic renal failure, giving account for 20% of renal transplants in children and adolescents in our country. In spite of the extensive research in the field, the mainstay of treatment for patients with HUS is supportive therapy, and there are no specific therapies preventing or ameliorating the disease course. In this review, we present the current knowledge about pathogenic mechanisms and discuss traditional and innovative therapeutic approaches, with special focus in national status and contributions made by Argentinean groups.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Escherichia coli Shiga-Toxigénica
/
Síndrome Hemolítico-Urémico
Tipo de estudio:
Etiology_studies
Límite:
Humans
País/Región como asunto:
America do sul
/
Argentina
Idioma:
Es
Revista:
Medicina (B Aires)
Año:
2011
Tipo del documento:
Article
País de afiliación:
Argentina
Pais de publicación:
Argentina