Human milk probiotic Lactobacillus fermentum CECT5716 reduces the incidence of gastrointestinal and upper respiratory tract infections in infants.
J Pediatr Gastroenterol Nutr
; 54(1): 55-61, 2012 Jan.
Article
en En
| MEDLINE
| ID: mdl-21873895
OBJECTIVES: The aim of the study was to examine the effects of a follow-on formula containing Lactobacillus fermentum CECT5716 (L. fermentum) on the incidence of infections in infants between the ages of 6 and 12 months. PATIENTS AND METHODS: A randomized double-blinded controlled study including infants at the age of 6 months was conducted. Infants were assigned randomly to either follow-on formula supplemented with L. fermentum plus galactooligosaccharide (experimental group, EG), or the same formula supplemented with only galactooligosaccharide (control group, CG). The main outcome was the incidence of infections for the 6-month duration of the study. RESULTS: The EG showed a significant 46% reduction in the incidence rate (IR) of gastrointestinal infections (EG: 0.196â±â0.51, CG: 0.363â±â0.53, IR ratio 0.54, 95% confidence interval [CI] 0.307-0.950, Pâ=â0.032), 27% reduction in the incidence of upper respiratory tract infections (EG: 0.969â±â0.96, CG: 1.330â±â1.23, IR ratio 0.729, 95% CI 0.46-1.38, Pâ=â0.026), and 30% reduction in the total number of infections (EG: 1.464â±â1.15, CG: 2.077â±â1.59, IR ratio 0.70, 95% CI 0.46-1.38, Pâ=â0.003), at the end of the study period compared with CG. CONCLUSIONS: Administration of a follow-on formula with L. fermentum CECT5716 may be useful for the prevention of community-acquired gastrointestinal and upper respiratory infections.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones del Sistema Respiratorio
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Probióticos
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Fórmulas Infantiles
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Limosilactobacillus fermentum
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Microbiología de Alimentos
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Enfermedades Gastrointestinales
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Leche Humana
Tipo de estudio:
Clinical_trials
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Incidence_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Female
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Humans
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Infant
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Male
Idioma:
En
Revista:
J Pediatr Gastroenterol Nutr
Año:
2012
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
Estados Unidos