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The use of Helicobacter pylori stool antigen test for the diagnosis of Helicobacter pylori in Lagos, Nigeria.
Smith, S I; Oyedeji, K S; Goodluck, H A; Fowora, M A; Anomneze, E; Lesi, O A.
Afiliación
  • Smith SI; Molecular Biology and Biotechnology Division, Nigerian Institute of Medical Research, PMB 2013, Yaba, Logos, Nigeria. stellaismith@yahoo.com
West Indian Med J ; 60(1): 33-5, 2011 Jan.
Article en En | MEDLINE | ID: mdl-21809708
OBJECTIVES: This study was carried out to screen the use of Helicobacter pylori stool antigen (HpSA) tests for diagnosis and monitoring of H pylori in Nigeria. METHODS: Seven hundred and forty participants were enrolled after informed consent was obtained, while 83 came back for a post-eradication test. The stool samples were taken from the patients at endoscopy and tested for HpSA. RESULTS: The proportion of patients that were positive at the pretest, 520 (70.3%) was significantly higher (Fisher's exact p = 0.001) than those positive at the post-test, 44 (53%). There was a significant difference (F = 4.106, p = 0.043) between the mean age of those that came for the pretest (40.0 +/- 14.5 years) and those that came for the post-test, 43.6 +/- 11.6 years. More males than females had the tendency to come back for a post-eradication test. CONCLUSION: Although potential bias was introduced during this study, HpSA using monoclonal antibody could still be used for diagnosis and monitoring of H pylori in Nigeria.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Helicobacter pylori / Infecciones por Helicobacter / Heces / Antígenos Bacterianos Tipo de estudio: Diagnostic_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: West Indian Med J Año: 2011 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Jamaica
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Helicobacter pylori / Infecciones por Helicobacter / Heces / Antígenos Bacterianos Tipo de estudio: Diagnostic_studies Límite: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: West Indian Med J Año: 2011 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Jamaica