Efficient synthesis of dissymmetric malonic acid S,O-esters via monoalcoholysis of symmetric dithiomalonates under neutral conditions.
Org Lett
; 13(16): 4406-9, 2011 Aug 19.
Article
en En
| MEDLINE
| ID: mdl-21790154
A novel method for the highly selective synthesis of dissymmetric S,O-malonates starting from symmetric diphenyl dithiomalonates under neutral conditions is described. The key step is the thermal formation of an acylketene, the stability of which would contribute to the selectivity. The synthetic utility of the dissymmetric S,O-malonates is also shown.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Estados Unidos