[Microsatellite instability and loss of heterozygosity in cancer].

Didziapetriene, Janina; Kanopiene, Daiva; Valuckas, Konstantinas Povilas; Uleckiene, Saule; Atkocius, Vydmantas; Micke, Ingrida; Suziedelis, Kestutis

[Microsatellite instability and loss of heterozygosity in cancer]. / Mikrosatelitu nestabilumas ir heterozigotiskumo praradimas sergant veziu.

Didziapetriene, Janina; Kanopiene, Daiva; Valuckas, Konstantinas Povilas; Uleckiene, Saule; Atkocius, Vydmantas; Micke, Ingrida; Suziedelis, Kestutis.

Afiliación

Didziapetriene J; Institute of Oncology, Vilnius University, Santariskiu, Lithuania. janina.didziapetriene@vuoi.lt

Medicina (Kaunas) ; 47(2): 125-35, 2011.

Article en Lt | MEDLINE | ID: mdl-21734447

RESUMEN

Literature review on genetic alterations (microsatellite instability and loss of heterozygosity) in different types of cancer is presented. Microsatellite instability and loss of heterozigosity are significant processes in carcinogenesis. The evaluation of microsatellite instability in cancer patients might be of clinical importance as a prognostic and predictive factor. The most of up-to-date data available are on microsatellite instability in colorectal cancer. For other types of cancer, the number of publications on microsatellite instability is rapidly increasing.

Asunto(s)

Pérdida de Heterocigocidad; Inestabilidad de Microsatélites; Neoplasias/genética; Neoplasias Colorrectales/genética; Humanos

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pérdida de Heterocigocidad / Inestabilidad de Microsatélites / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: Lt Revista: Medicina (Kaunas) Asunto de la revista: MEDICINA Año: 2011 Tipo del documento: Article País de afiliación: Lituania Pais de publicación: Suiza

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