[The trigger function of cAMP in regulating the chemiluminescence of macrophages exposed to ethanol]. / Triggernaia funktsiia tsAMF v reguliatsii khemiliuminestsentsii makrofagov pri vozdeistvii étanola.
Tsitologiia
; 32(4): 387-90, 1990.
Article
en Ru
| MEDLINE
| ID: mdl-2173182
The capacity of mouse peritoneal macrophages to luminol-dependent zymosan-induced chemiluminescence was investigated. It was revealed that a short-term incubation (5-10 min) of macrophages in 0.05-0.50% ethanol resulted in a dose-dependent reduction of chemiluminescent response. Ethanol induce a sharp 2-3 fold increase in the intracellular cAMP content after a 2 minutes incubation. The temporal and concentration correlation of both the processes suggests that the inhibition of chemiluminescence may be mediated by the intracellular cAMP content.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
AMP Cíclico
/
Etanol
/
Mediciones Luminiscentes
/
Macrófagos
Límite:
Animals
Idioma:
Ru
Revista:
Tsitologiia
Año:
1990
Tipo del documento:
Article
Pais de publicación:
Rusia