Cost-effectiveness of screening for abdominal aortic aneurysm in the Netherlands and Norway.
Br J Surg
; 98(11): 1546-55, 2011 Nov.
Article
en En
| MEDLINE
| ID: mdl-21725968
BACKGROUND: The aim of this study was to determine the cost-effectiveness of ultrasound screening for abdominal aortic aneurysm (AAA) in men aged 65 years, for both the Netherlands and Norway. METHODS: A Markov model was developed to simulate life expectancy, quality-adjusted life-years, net health benefits, lifetime costs and incremental cost-effectiveness ratios for both screening and no screening for AAA. The best available evidence was retrieved from the literature and combined with primary data from the two countries separately, and analysed from a national perspective. A threshold willingness-to-pay (WTP) of 20,000 and 62,500 was used for data from the Netherlands and Norway respectively. RESULTS: The additional costs of the screening strategy compared with no screening were 421 (95 per cent confidence interval 33 to 806) per person in the Netherlands, and the additional life-years were 0·097 (-0·180 to 0·365), representing 4340 per life-year. For Norway, the values were 562 (59 to 1078), 0·057 (-0·135 to 0·253) life-years and 9860 per life-year respectively. In Norway the results were sensitive to a decrease in the prevalence of AAA in 65-year-old men to 1 per cent, or lower. Probabilistic sensitivity analyses indicated that AAA screening has a 70 per cent probability of being cost-effective in the Netherlands with a WTP threshold of 20,000, and 70 per cent in Norway with a threshold of 62,500. CONCLUSION: Using this model, screening for AAA in 65-year-old men would be highly cost-effective in both the Netherlands and Norway.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Rotura de la Aorta
/
Tamizaje Masivo
/
Aneurisma de la Aorta Abdominal
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Health_economic_evaluation
/
Risk_factors_studies
/
Screening_studies
Aspecto:
Patient_preference
Límite:
Aged
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
Br J Surg
Año:
2011
Tipo del documento:
Article
País de afiliación:
Países Bajos
Pais de publicación:
Reino Unido