Nucleolar organizer regions and Ki-67 immunostaining in ductal breast cancer: a comparative study.
Pathologica
; 82(1078): 125-32, 1990.
Article
en En
| MEDLINE
| ID: mdl-2168032
53 cases of invasive ductal (NOS) carcinomas of the breast were studied by means of an immunostaining method with Ki-67 monoclonal antibody and an argyrophilic method for the demonstration of Nucleolar Organizer Regions (AgNORs). The percentage of cancer cells with nuclear Ki-67 immunoreactivity and the mean number of NORs for each tumour were statistically related. The data obtained showed a good correlation between Ki-67 index and NOR score (rS = 0.47 - P less than 0.001). The authors suggest that the AgNOR method--which is applicable to routinely processed material--might effectively substitute Ki-67 immunostaining as a marker of cell proliferation in ductal breast cancer.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Mama
/
Carcinoma Intraductal no Infiltrante
/
Anticuerpos Monoclonales
/
Antígenos de Neoplasias
/
Región Organizadora del Nucléolo
Límite:
Adult
/
Aged
/
Aged80
/
Humans
/
Middle aged
Idioma:
En
Revista:
Pathologica
Año:
1990
Tipo del documento:
Article
Pais de publicación:
Italia