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Blood group A isoagglutinins in A(2) → O simultaneous liver/kidney transplantation may not influence kidney function.
Bryan, C F; Abdulkarim, B; Nawabi, A; Stewart, D; Yarlagadda, S G.
Afiliación
  • Bryan CF; Midwest Transplant Network Laboratory, Westwood, KS, USA. cbryan@mwtn.org
Am J Transplant ; 11(7): 1527-30, 2011 Jul.
Article en En | MEDLINE | ID: mdl-21668637
We simultaneously transplanted a liver and kidney (SLK) into a 55-year-old woman with end-stage liver disease secondary to recurrent primary biliary cirrhosis. The patient was blood group O, the donor was A(2) (A, non-A1) and the patient's A isoagglutinin titer was 512. Good renal function was evident by normalization of her creatinine values following transplantation. Recovery was unremarkable and she was discharged on post op day 9. The patient has not experienced an episode of rejection in either organ during the 6 months of follow-up. This case is important because high A IgG isoagglutinin levels (8 or higher) in kidney alone A(2) → O transplantation are detrimental to outcome but do not affect outcome in liver alone A(2) → O transplants; however, no such anti-A titer data have been published for A(2) → O (or B) SLK transplantation.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Incompatibilidad de Grupos Sanguíneos / Sistema del Grupo Sanguíneo ABO / Trasplante de Riñón / Trasplante de Hígado / Riñón Límite: Female / Humans / Middle aged Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2011 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Incompatibilidad de Grupos Sanguíneos / Sistema del Grupo Sanguíneo ABO / Trasplante de Riñón / Trasplante de Hígado / Riñón Límite: Female / Humans / Middle aged Idioma: En Revista: Am J Transplant Asunto de la revista: TRANSPLANTE Año: 2011 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos