Antibody responses to Herpesvirus papio antigens in baboons with lymphoma.
Int J Cancer
; 23(2): 186-92, 1979 Feb.
Article
en En
| MEDLINE
| ID: mdl-216640
An Epstein-Barr virus-related herpesvirus, termed Herpesvirus papio (HVP), was isolated from baboons (Papio hamadryas) at the Institute of Experimental Pathology and Therapy, Sukhumi, USSR, where there is a continuing outbreak of lymphoma. In the present study sera from diseased baboons and from age- and sex-matched control animals were examined for antibodies to HVP antigens. Results showed that animals with lymphoid disease had antibodies to HVP virus capsid, early, soluble, and nuclear antigens at higher frequencies and at higher titers than did control animals. Antibody titers were not age- or sex-related. No concordancy was detected for antibodies to soluble and nuclear antigens. The sera were also examined for antibodies to two other widely distributed viruses of hamadryas baboons, cytomegalovirus and foamy virus. The results of these studies did not indicate a disease-related role for either of these viruses.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Herpesviridae
/
Linfoma
/
Anticuerpos Antivirales
Límite:
Animals
Idioma:
En
Revista:
Int J Cancer
Año:
1979
Tipo del documento:
Article
Pais de publicación:
Estados Unidos