Treatment of renal cell carcinoma with intra-arterial administration of SMANCS dissolved in Lipiodol.
Anticancer Res
; 10(3): 709-15, 1990.
Article
en En
| MEDLINE
| ID: mdl-2164351
Patients 1 with an unresectable clear-cell carcinoma of the kidney was treated by intra-arterial administration of SMANCS dissolved in an oily medium, Lioidol, (SMANCS/Lipiodol). It was previously shown that targeting chemotherapy could be achieved for hepatoma by the arterially administered SMANCS/Lipiodol. In this study, SMANCS/Lipiodol was administered for renal cancer and the selective remaining of SMANCS/Lipiodol in renal cancer was observed in this patient. Patient 1, after three years and five months of repeated arterial injection of the drug, the patient's physical condition recovered sufficiently, reduction in tumor size was observed and the tumor became resectable. Patient 2 with renal carcinoma (4 cm in diameter) was treated by intra-arterial injection of SMANCS/Lipiodol and resected for prevention of postoperative recurrence. More than 90% of the tumor showed necrosis. Definite anticancer effects of the preoperative arterial administration of SMANCS/Lipiodol can be observed both clinically and histologically.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Poliestirenos
/
Carcinoma de Células Renales
/
Cinostatina
/
Furanos
/
Neoplasias Renales
/
Anhídridos Maleicos
/
Antibióticos Antineoplásicos
/
Antineoplásicos
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Anticancer Res
Año:
1990
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Grecia