Chronic myeloid leukemia treated with busulfan.
Oncol Rep
; 3(6): 1067-9, 1996 Nov.
Article
en En
| MEDLINE
| ID: mdl-21594509
Interferon alpha is presently viewed as the first choice drug for treatment of chronic myeloid leukemia; however patients who are not eligible for this type of therapy are still treated with conventional chemotherapeutic agents as for instance hydroxyurea and/or busulfan. In a series of 23 patients with Philadelphia chromosome positive chronic myeloid leukemia who have been treated solely with busulfan, we have evaluated the relationship between total amount of drug required during the first 12 months of treatment and duration of the chronic phase. A statistically significant (p<0.005) inverse relationship between these two parameters was found, indicating that patients with low busulfan requirement during the first year of therapy have a better prognosis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Oncol Rep
Asunto de la revista:
NEOPLASIAS
Año:
1996
Tipo del documento:
Article
Pais de publicación:
Grecia