Cancer-targeting multifunctionalized gold nanoparticles in imaging and therapy.

Jiao, P F; Zhou, H Y; Chen, L X; Yan, B

Jiao, P F; Zhou, H Y; Chen, L X; Yan, B.

Afiliación

Jiao PF; School of Chemistry and Chemical Engineering Shandong University, Jinan, Shandong, 250100, China.

Curr Med Chem ; 18(14): 2086-102, 2011.

Article en En | MEDLINE | ID: mdl-21517767

RESUMEN

Nanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.

Asunto(s)

Oro/uso terapéutico; Nanopartículas/uso terapéutico; Neoplasias/diagnóstico; Neoplasias/tratamiento farmacológico; Animales; Oro/química; Humanos; Nanomedicina/métodos; Nanopartículas/química; Nanotecnología/métodos

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nanopartículas / Oro / Neoplasias Límite: Animals / Humans Idioma: En Revista: Curr Med Chem Asunto de la revista: QUIMICA Año: 2011 Tipo del documento: Article País de afiliación: China Pais de publicación: Emiratos Árabes Unidos

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