Can the contra-lateral limb be used as a control with respect to analyses of bone remodelling?
Med Eng Phys
; 33(8): 987-92, 2011 Oct.
Article
en En
| MEDLINE
| ID: mdl-21497542
Bone loss may result from remodelling initiated by implant stress protection. Quantifying remodelling requires bone density distributions which can be obtained from computed tomography scans. Pre-operative scans of large animals however are rarely possible. This study aimed to determine if the contra-lateral bone is a suitable control for the purpose of quantifying bone remodelling. CT scans of 8 pairs of ovine tibia were used to determine the likeness of left and right bones. The deviation between the outer surfaces of the bone pairs was used to quantify geometric similarity. The density differences were determined by dividing the bones into discrete volumes along the shaft of the tibia. Density differences were also determined for fractured and contra-lateral bone pairs to determine the magnitude of implant related remodelling. Left and right ovine tibiae were found to have a high degree of similarity with differences of less than 1.0mm in the outer surface deviation and density difference of less than 5% in over 90% of the shaft region. The density differences (10-40%) as a result of implant related bone remodelling were greater than left-right differences. Therefore, for the purpose of quantifying bone remodelling in sheep, the contra-lateral tibia may be considered an alternative to a pre-operative control.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tibia
/
Tomografía Computarizada por Rayos X
/
Remodelación Ósea
Límite:
Animals
Idioma:
En
Revista:
Med Eng Phys
Asunto de la revista:
BIOFISICA
/
ENGENHARIA BIOMEDICA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Australia
Pais de publicación:
Reino Unido