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Reproduction and age of onset of Huntington's disease in Tasmania.
Pridmore, S A; Pridmore, H D; Adams, G C.
Afiliación
  • Pridmore SA; Department of Psychiatry, University of Tasmania Clinical School, Hobart.
Med J Aust ; 153(10): 589-92, 1990 Nov 19.
Article en En | MEDLINE | ID: mdl-2146465
This study demonstrates that in Tasmania, individuals born before 1930, with an onset of Huntington's disease (HD) after the mean age of onset, were significantly more fertile than their unaffected siblings and the general population. This applied to both sexes. The mean parental age of men with late-onset disease was significantly greater than that of their unaffected male siblings. The clinical implication is that those individuals at 50% risk of late-onset HD who have achieved their desired family size should be offered sterilisation.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Composición Familiar / Enfermedad de Huntington / Fertilidad Límite: Female / Humans / Male País/Región como asunto: Oceania Idioma: En Revista: Med J Aust Año: 1990 Tipo del documento: Article Pais de publicación: Australia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Composición Familiar / Enfermedad de Huntington / Fertilidad Límite: Female / Humans / Male País/Región como asunto: Oceania Idioma: En Revista: Med J Aust Año: 1990 Tipo del documento: Article Pais de publicación: Australia