Study of potential binding of biologically important sugars with a dinuclear cobalt(II) complex.
Carbohydr Res
; 346(6): 733-8, 2011 May 01.
Article
en En
| MEDLINE
| ID: mdl-21429479
The investigation of the sugar-metal ion interactions remains one of the main objectives of carbohydrate coordination chemistry because the interactions between metal ions and carbohydrates are involved in many biochemical processes. The potential binding interaction between a five-coordinate dinuclear cobalt(II) complex, Na(2)[Co(2)(tcdc)(µ-OAc)] (1) [Na(5)tcdc=Sodium-N,N,N',N'-tetrakis(sodium carboxylate methyl)-2,6-diaminocresolate] and biologically important sugar substrates (D-glucose, D-xylose, and D-mannose) has been studied. In alkaline media, the complex 1 shows an excellent chelating ability toward these sugar substrates. A combined approach of FTIR and UV-vis spectroscopic investigations shows that the complex forms a 1:1 complex/substrate-bound product. UV-vis spectra indicate a significant blue-shift of the absorption maximum of metal complex during carbohydrate coordination highlighting the sugar binding ability of complex 1. The apparent binding constants of the substrate-bound cobalt(II) complexes have been determined from the UV-vis titration experiments.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Carbohidratos
/
Cobalto
Idioma:
En
Revista:
Carbohydr Res
Año:
2011
Tipo del documento:
Article
País de afiliación:
India
Pais de publicación:
Países Bajos