Gene discovery in Triatoma infestans.
Parasit Vectors
; 4: 39, 2011 Mar 18.
Article
en En
| MEDLINE
| ID: mdl-21418565
BACKGROUND: Triatoma infestans is the most relevant vector of Chagas disease in the southern cone of South America. Since its genome has not yet been studied, sequencing of Expressed Sequence Tags (ESTs) is one of the most powerful tools for efficiently identifying large numbers of expressed genes in this insect vector. RESULTS: In this work, we generated 826 ESTs, resulting in an increase of 47% in the number of ESTs available for T. infestans. These ESTs were assembled in 471 unique sequences, 151 of which represent 136 new genes for the Reduviidae family. CONCLUSIONS: Among the putative new genes for the Reduviidae family, we identified and described an interesting subset of genes involved in development and reproduction, which constitute potential targets for insecticide development.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Triatoma
/
Etiquetas de Secuencia Expresada
/
Vectores de Enfermedades
/
Estudios de Asociación Genética
Límite:
Animals
País/Región como asunto:
America do sul
/
Argentina
Idioma:
En
Revista:
Parasit Vectors
Año:
2011
Tipo del documento:
Article
País de afiliación:
Argentina
Pais de publicación:
Reino Unido