[Methemoglobinemia in patients with Plasmodium vivax receiving oral therapy with primaquine]. / Metemoglobinemia em pacientes com malária por Plasmodium vivax em uso oral de primaquina.
Rev Soc Bras Med Trop
; 44(1): 113-5, 2011.
Article
en Pt
| MEDLINE
| ID: mdl-21340422
INTRODUCTION: Primaquine can produce adverse reactions as toxicity to blood when used in the treatment of vivax malaria. This work aimed to determine methemoglobinemia in patients with vivax malaria receiving oral therapy with primaquine. METHODS: Spectrophotometric quantification of methemoglobinemia and qualitative assay for glucose-6-phosphate dehydrogenase. RESULTS: Methemoglobinemia ranged from 2.85 to 5.45% in male patients and 3.77 to 7.34% in female patients. CONCLUSIONS: A statistically significant increase in methemoglobinemia was observed following oral therapy with primaquine, with no clinical manifestations, and independent of sex and the qualitative expression of glucose-6-phosphate dehydrogenase.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Primaquina
/
Malaria Vivax
/
Glucosafosfato Deshidrogenasa
/
Metahemoglobinemia
/
Antimaláricos
Tipo de estudio:
Observational_studies
/
Qualitative_research
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Pt
Revista:
Rev Soc Bras Med Trop
Año:
2011
Tipo del documento:
Article
Pais de publicación:
Brasil