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An opinion and practice survey on the structure and management of data and safety monitoring boards.
Tereskerz, Patti M; Guterbock, Thomas M; Kermer, Deborah A; Moreno, Jonathan D.
Afiliación
  • Tereskerz PM; Program in Ethics and Policy, Center for Biomedical Ethics and Humanities, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA. pjm7s@virginia.edu
Account Res ; 18(1): 1-30, 2011 Jan.
Article en En | MEDLINE | ID: mdl-21287412
There is little to no empirical data available on how data and safety monitoring boards (DSMBs) are structured and how they operate. The purpose of this study was to provide data on this. To accomplish this goal, we administered a random survey on current structure and management practices and opinions as reported by principal investigators (PIs) and biostatisticians. We also surveyed Institutional Review Board (IRB) community members, as proxies for the public, as to their opinions on how DSMBs should be structured and managed. A final purpose was to compare opinions about what should be taking place to what is actually happening.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pautas de la Práctica en Medicina / Comités de Ética en Investigación / Comités de Monitoreo de Datos de Ensayos Clínicos / Testimonio de Experto Tipo de estudio: Evaluation_studies / Qualitative_research Límite: Female / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Account Res Asunto de la revista: ETICA Año: 2011 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pautas de la Práctica en Medicina / Comités de Ética en Investigación / Comités de Monitoreo de Datos de Ensayos Clínicos / Testimonio de Experto Tipo de estudio: Evaluation_studies / Qualitative_research Límite: Female / Humans / Male País/Región como asunto: America do norte Idioma: En Revista: Account Res Asunto de la revista: ETICA Año: 2011 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos