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Interactions between nerve agent pretreatment and drugs commonly used in combat anesthesia.
Keeler, J R.
Afiliación
  • Keeler JR; Pathophysiology Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Grounds, MD.
Mil Med ; 155(11): 527-33, 1990 Nov.
Article en En | MEDLINE | ID: mdl-2126852
Pyridostigmine is a drug stockpiled for oral pretreatment of nerve agent exposure; however, the soldier is still vulnerable to conventional warfare injuries, which are commonly associated with the need for anesthesia and surgery. In order to determine if we should be concerned about pyridostigmine-drug interactions, a comprehensive search of existing literature on pyridostigmine and selected drugs contained in the Defense Medical Standardization Board D-Day Items list was completed. It appears that the most significant interaction might be with the neuromuscular blocking drugs used in anesthesia, which in turn could pose the greatest casualty management concerns. Other potential interactions are discussed, along with a review of the pharmacology of pyridostigmine.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bromuro de Piridostigmina / Guerra Química / Anestésicos Límite: Humans Idioma: En Revista: Mil Med Año: 1990 Tipo del documento: Article Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bromuro de Piridostigmina / Guerra Química / Anestésicos Límite: Humans Idioma: En Revista: Mil Med Año: 1990 Tipo del documento: Article Pais de publicación: Reino Unido