Genotoxic effects of aluminum, iron and manganese in human cells and experimental systems: a review of the literature.

Lima, P D L; Vasconcellos, M C; Montenegro, R C; Bahia, M O; Costa, E T; Antunes, L M G; Burbano, R R

Lima, P D L; Vasconcellos, M C; Montenegro, R C; Bahia, M O; Costa, E T; Antunes, L M G; Burbano, R R.

Afiliación

Lima PD; Molecular Biology Laboratory, Center of Biological and Health Sciences, Estadual University of Pará, Belém/PA, Brazil.

Hum Exp Toxicol ; 30(10): 1435-44, 2011 Oct.

Article en En | MEDLINE | ID: mdl-21247993

RESUMEN

There is considerable evidence indicating an increase in neurodegenerative disorders in industrialized countries. The clinical symptoms and the possible mutagenic effects produced by acute poisoning and by chronic exposure to metals are of major interest. This study is a review of the data found concerning the genotoxic potential of three metals: aluminum (Al), iron (Fe) and manganese (Mn), with emphasis on their action on human cells.

Asunto(s)

Aluminio/toxicidad; Hierro/toxicidad; Manganeso/toxicidad; Mutágenos/toxicidad; Animales; Células Cultivadas; Aberraciones Cromosómicas/inducido químicamente; Humanos; Mutación

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aluminio / Hierro / Manganeso / Mutágenos Límite: Animals / Humans Idioma: En Revista: Hum Exp Toxicol Asunto de la revista: TOXICOLOGIA Año: 2011 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido

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