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The point prevalence of clinically relevant primary Sjögren's syndrome in two Norwegian counties.
Gøransson, L G; Haldorsen, K; Brun, J G; Harboe, E; Jonsson, M V; Skarstein, K; Time, K; Omdal, R.
Afiliación
  • Gøransson LG; Clinical Immunology Unit, Department of Internal Medicine, Stavanger University Hospital, POB 8100, N-4068 Stavanger, Norway. gola@sus.no
Scand J Rheumatol ; 40(3): 221-4, 2011 May.
Article en En | MEDLINE | ID: mdl-21231797
OBJECTIVE: Primary Sjögren's syndrome (PSS) is a chronic autoimmune inflammatory disease characterized by exocrine gland inflammation producing clinical symptoms such as dryness of the mouth and eyes. The reported prevalence of PSS is variable, probably because of different classification criteria used and selection bias. The aim of this study was to determine the prevalence of PSS in a well-defined Norwegian Caucasian population using the revised American-European Consensus Group (AECG) criteria. METHODS: Three hospitals and three private rheumatology practices provide all of the rheumatology services to the local population in Hordaland and Rogaland counties, which included 852 342 Caucasian inhabitants as of 1 January 2009. Patients on file fulfilling the new revised AECG criteria for PSS were included, and patients with incomplete data were invited to a screening visit. RESULTS: A total of 424 PSS patients were identified. Their mean age was 61.6 ± 13.2 years; 28 (7%) were men and 396 (93%) were women. The point estimate for the proportion of PSS was 0.050% [95% confidence interval (CI) 0.048-0.052]. CONCLUSION: The prevalence of PSS in this Norwegian population of Caucasians is lower than previously reported when less stringent criteria for identifying PSS were used, but is in line with more recent studies using the same criteria and methods as in this study.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Sjögren Tipo de estudio: Diagnostic_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Scand J Rheumatol Año: 2011 Tipo del documento: Article País de afiliación: Noruega Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de Sjögren Tipo de estudio: Diagnostic_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Scand J Rheumatol Año: 2011 Tipo del documento: Article País de afiliación: Noruega Pais de publicación: Reino Unido