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Neurocognitive recovery in SMART syndrome: a case report.
Bradshaw, Jennifer; Chen, Luke; Saling, Michael; Fitt, Greg; Hughes, Andrew; Dowd, Ariane.
Afiliación
  • Bradshaw J; Neurosciences Department, University of Melbourne, Heidelberg 3084, Victoria, Australia. jbrad@unimelb.edu.au
Cephalalgia ; 31(3): 372-6, 2011 Feb.
Article en En | MEDLINE | ID: mdl-21123627
INTRODUCTION: Stroke-like migraine attacks after radiation therapy, or SMART syndrome, is characterised by migraine-like headache with or without aura, transient neurological dysfunction, including seizures, and gyriform enhancement on magnetic resonance imaging (MRI) which resolves over a period of weeks. Detailed neuropsychological characterisation in SMART syndrome is lacking and there are no published data on the course and pattern of neurocognitive recovery. RESULTS: The acute clinical presentation was one of unstable, fluctuating neurocognitive disturbances, complicated by seizure activity, followed by a longer term lag in the recovery of focal neuropsychological deficits which, we believe, was due to the more slowly resolving cerebral effects of SMART. CONCLUSIONS: To our knowledge, this is the first case of SMART syndrome in which neuropsychological functioning has been comprehensively and serially examined. This case is also unique due to the development of complex partial seizures. We suggest that epileptiform activity during clinical seizures should not be regarded as inconsistent with a diagnosis of SMART, provided that the seizures do not explain the onset of the other clinical and radiological features.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Radioterapia / Encéfalo / Trastornos del Conocimiento Tipo de estudio: Etiology_studies Límite: Adult / Humans / Male Idioma: En Revista: Cephalalgia Año: 2011 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Radioterapia / Encéfalo / Trastornos del Conocimiento Tipo de estudio: Etiology_studies Límite: Adult / Humans / Male Idioma: En Revista: Cephalalgia Año: 2011 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido