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A fatal case of paraquat ingestion: clinical course and review of pathophysiology.
Olson, Douglas P; Diaz, Juan A; Jereda, Jose Dalio Gomez.
Afiliación
  • Olson DP; Hospital Tela Integrado, Tela, Honduras. Douglas.olson@yale.edu
Med Sci Monit ; 16(12): CS153-6, 2010 Dec.
Article en En | MEDLINE | ID: mdl-21119584
BACKGROUND: Exposure to the dipyridyl herbicide paraquat can cause many manifestations of toxicity, and is a common method of suicide in developing countries. CASE REPORT: We present a case of a 20 year old healthy gentleman who intentionally overdosed on paraquat in a suicide attempt. He presented to the hospital within 4 hours of ingestion. Despite standard supportive measures, the patient's clinical condition worsened. He developed ulceration of his oral mucosa. He also developed acute non-oliguric renal failure and acute liver injury. After his mental status began to deteriorate, the patient expired. CONCLUSIONS: There are several therapies that may have helped this patient's condition. An explanation about the pathophysiology of toxicity and updated information on treatment is provided for this common condition with poor prognosis.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Paraquat / Suicidio / Quemaduras Químicas / Insuficiencia Renal / Enfermedad Hepática Inducida por Sustancias y Drogas Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Med Sci Monit Asunto de la revista: MEDICINA Año: 2010 Tipo del documento: Article País de afiliación: Honduras Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Paraquat / Suicidio / Quemaduras Químicas / Insuficiencia Renal / Enfermedad Hepática Inducida por Sustancias y Drogas Tipo de estudio: Prognostic_studies Límite: Adult / Humans / Male Idioma: En Revista: Med Sci Monit Asunto de la revista: MEDICINA Año: 2010 Tipo del documento: Article País de afiliación: Honduras Pais de publicación: Estados Unidos