Synchronous occurrence of extramedullary plasmacytoma and squamous cell carcinoma in situ in the larynx: a case report.
Chin J Cancer
; 29(12): 1029-34, 2010 Dec.
Article
en En
| MEDLINE
| ID: mdl-21114925
Extramedullary plasmacytoma of the larynx is rare, especially when coexisted with squamous cell carcinoma in situ. We report a 56-year-old woman with hoarseness for 6 months and dysphonia for a week. Fiberoptic laryngoscopic examination showed a red, smooth-surface swelling in the submucous region of the left ventricle and ventricular band of the larynx. The patient underwent vertical laryngectomy and modified left neck dissection. Postoperative pathologic examination revealed coexisting plasmacytoma and carcinoma in situ. Bone marrow biopsy and systemic radiogram showed no positive findings. The hepatic and renal functions were normal. Monoclonal immunoglobulin light chain of type kappa was detected in urine. Hence, a laryngeal extramedullary plasmacytoma with carcinoma in situ was diagnosed. No recurrence or progression was observed during a 2-year follow-up. Here, we discussed the risk factors, diagnosis, and therapy for this rare disease.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plasmacitoma
/
Carcinoma in Situ
/
Carcinoma de Células Escamosas
/
Neoplasias Laríngeas
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Chin J Cancer
Asunto de la revista:
NEOPLASIAS
Año:
2010
Tipo del documento:
Article
Pais de publicación:
Reino Unido