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Diode array detection of low level co-eluting species in high-performance liquid chromatography.
Anderson, N H; Gray, M R; Hinds, C J.
Afiliación
  • Anderson NH; Sterling Research Group, Alnwick, Northumberland, UK.
J Pharm Biomed Anal ; 8(8-12): 853-7, 1990.
Article en En | MEDLINE | ID: mdl-2100632
A simple and sensitive method for detecting low levels (0.5 and 1.0%, w/w) of co-eluting species in HPLC has been developed. This method is based on the subtraction of normalized peak up-slope and down-slope spectra from that of the apex. Visual inspection of the resultant "difference spectra" allows for a qualitative judgement regarding the integrity of the peak under consideration.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromatografía Líquida de Alta Presión Tipo de estudio: Diagnostic_studies / Qualitative_research Idioma: En Revista: J Pharm Biomed Anal Año: 1990 Tipo del documento: Article Pais de publicación: Reino Unido
Buscar en Google
Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromatografía Líquida de Alta Presión Tipo de estudio: Diagnostic_studies / Qualitative_research Idioma: En Revista: J Pharm Biomed Anal Año: 1990 Tipo del documento: Article Pais de publicación: Reino Unido