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Trans fatty acids, insulin resistance and diabetes.
Thompson, A K; Minihane, A-M; Williams, C M.
Afiliación
  • Thompson AK; Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutrition Science, University of Reading, Reading, UK. a.k.thompson@reading.ac.uk
Eur J Clin Nutr ; 65(5): 553-64, 2011 May.
Article en En | MEDLINE | ID: mdl-20978530
The possible relationship between consumption of trans fatty acids (TFAs) and risk of insulin resistance or development of diabetes mellitus type II has been considered by a number of human and animal studies over the past decade. This review evaluates the evidence, and concludes that there is limited evidence for a weak association at high TFA intakes, but very little convincing evidence that habitual exposure as part of a standard western diet has a significant contribution to risk of diabetes or insulin resistance. The possibility of increased risk for individuals with particular genotypes (such as the FABP2 Thr54 allele) is of interest, but further work would be required to provide sufficient evidence of any association.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resistencia a la Insulina / Grasas de la Dieta / Ácidos Grasos trans / Diabetes Mellitus Tipo 2 Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Eur J Clin Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2011 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Resistencia a la Insulina / Grasas de la Dieta / Ácidos Grasos trans / Diabetes Mellitus Tipo 2 Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Eur J Clin Nutr Asunto de la revista: CIENCIAS DA NUTRICAO Año: 2011 Tipo del documento: Article Pais de publicación: Reino Unido