Cancer transmissibility across HLA barriers between immunocompetent individuals: rare but not impossible.
Hum Immunol
; 72(1): 1-4, 2011 Jan.
Article
en En
| MEDLINE
| ID: mdl-20951754
The axiom of human leukocyte incompatibility (HLA) incompatibility has always led scientists to consider cancer transmission between HLA-different individuals impossible. In fact, cancer transmission between individuals represents a frightening possibility in animal populations with limited HLA diversity or for rare cancers exploiting downregulation of HLA expression. We review here evidence from nonhuman models and settings for interhuman transmission.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tumores Venéreos Veterinarios
/
Antígenos de Histocompatibilidad Clase I
/
Inmunocompetencia
/
Neoplasias
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Hum Immunol
Año:
2011
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Estados Unidos