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An in vitro method for studying endocrine and exocrine secretion in the perfused isolated rabbit pancreas.
Fichaux, F; Catala, J; Bonnafous, R.
Afiliación
  • Fichaux F; Laboratoire de Physiologie de la Nutrition, Université Paul Sabatier, Toulouse, France.
Diabetes Res ; 13(2): 95-100, 1990 Feb.
Article en En | MEDLINE | ID: mdl-2091876
This work describes a perfusion technique adapted to the isolated rabbit pancreas allowing investigation of both the endocrine and exocrine function. The pancreas-duodenum-stomach-spleen complex is removed and perfused with a modified Krebs Ringer Bicarbonate medium. The surgical steps leading to the removal of the complex are described. The endocrine response is studied by measuring insulin release when the pancreas is submitted to successive glucose stimulations and the exocrine function is evaluated by the alpha-chymotrypsin activity of the pancreatic juice harvested during the perfusion.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Páncreas / Jugo Pancreático / Quimotripsina / Islotes Pancreáticos / Insulina Límite: Animals Idioma: En Revista: Diabetes Res Asunto de la revista: ENDOCRINOLOGIA Año: 1990 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Páncreas / Jugo Pancreático / Quimotripsina / Islotes Pancreáticos / Insulina Límite: Animals Idioma: En Revista: Diabetes Res Asunto de la revista: ENDOCRINOLOGIA Año: 1990 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido