Novel mechanisms of endothelial dysfunction in diabetes.

Yang, Guang; Lucas, Rudolf; Caldwell, Ruth; Yao, Lin; Romero, Maritza J; Caldwell, Robert W

Yang, Guang; Lucas, Rudolf; Caldwell, Ruth; Yao, Lin; Romero, Maritza J; Caldwell, Robert W.

Afiliación

Yang G; Department of Vascular Biology Center, Medical College of Georgia, Augusta, GA, USA.

J Cardiovasc Dis Res ; 1(2): 59-63, 2010 Apr.

Article en En | MEDLINE | ID: mdl-20877687

RESUMEN

Diabetes mellitus is a major risk factor for cardiovascular morbidity and mortality. This condition increases the risk of developing coronary, cerebrovascular, and peripheral arterial disease fourfold. Endothelial dysfunction is a major contributor to the pathogenesis of vascular disease in diabetes mellitus patients and has recently received increased attention. In this review article, some recent developments that could improve the knowledge of diabetes-induced endothelial dysfunction are discussed.

Palabras clave

Arginase; diabetes; endothelial dysfunction; protein kinase C; reactive oxygen species; tumor necrosis factor

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Cardiovasc Dis Res Año: 2010 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: India

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