Long-range protein coupling mediated by critical low-energy modes of tubular lipid membranes.
Phys Rev Lett
; 105(2): 028102, 2010 Jul 09.
Article
en En
| MEDLINE
| ID: mdl-20867743
We develop a theory of a resonant effect in protein-membrane coupling taking place in the vicinity of instabilities in tubular lipid membranes (TLMs) under longitudinal force and pressure difference constraints. Two critical low-energy modes defining the stability domain boundaries are found. We show that these modes mediate long-range TLM-protein coupling and interactions between absorbed proteins. Besides, TLM mechanical instabilities strongly influence protein desorption and protein cluster nucleation on TLMs. Model predictions can be tested over a large spectrum of mechanochemical conditions.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas
/
Lípidos de la Membrana
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Phys Rev Lett
Año:
2010
Tipo del documento:
Article
País de afiliación:
Francia
Pais de publicación:
Estados Unidos