Primary intracranial leiomyosarcoma in an HIV-infected patient.
Int J Clin Oncol
; 16(1): 63-6, 2011 Feb.
Article
en En
| MEDLINE
| ID: mdl-20676716
Primary intracranial leiomyosarcomas are rare tumors arising from the mesenchymal cells of the dura matter or the cerebral blood vessels. Only 14 cases of primary intracranial leiomyosarcoma are reported in the literature. We report a case of primary intracranial leiomyosarcoma in an human immunodeficiency virus-positive patient with a CD4 count of 14 cells/µL. Additionally, in-situ hybridization of Epstein-Barr virus (EBV) early RNA stained sections highlighted the tumor cells, consistent with the presence of EBV. Review of the literature strongly suggests an association between AIDS, EBV, and primary intracranial leiomyosarcoma. Given the paucity of information in the literature, we review possible chemotherapeutic agents for treatment of primary intracranial leiomyosarcoma in patients refractory to surgical resection and radiation therapy.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Encefálicas
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Síndrome de Inmunodeficiencia Adquirida
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Herpesvirus Humano 4
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Infecciones por Virus de Epstein-Barr
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Leiomiosarcoma
Límite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Int J Clin Oncol
Asunto de la revista:
NEOPLASIAS
Año:
2011
Tipo del documento:
Article
Pais de publicación:
Japón