The institutional review board.
Semin Nucl Med
; 40(5): 385-92, 2010 Sep.
Article
en En
| MEDLINE
| ID: mdl-20674597
Several ethical transgressions involving human subjects in scientific research during the last century have led to guidelines for acceptable research conduct and oversight. Thoughtful examination of these events yielded ethical documents whose principles eventually became codified into federal regulations governing research. These regulations specify the composition and function of the institutional review board (IRB), as well as the criteria by which the IRB judges the acceptability of proposed research. Continuous advances in medicine and technology generate the need to test new and potentially viable interventions for safety and efficacy. These advances in medical science rely heavily on the altruism and sometimes heroism of individuals who put their own well being at risk for the benefit of others by participating in clinical research experiments. It is therefore necessary for researchers to understand the function of the IRB and ethics review committees from which approval is required before research in human subjects may begin. Understanding the function of the IRB requires an appreciation for the rules by which it is governed, as well as the history and circumstances that influenced the creation of those rules. Researchers who appreciate the IRB's purpose will be better equipped to navigate the labyrinth of research guidelines and regulations.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Comités de Ética en Investigación
Tipo de estudio:
Guideline
/
Prognostic_studies
Aspecto:
Ethics
Límite:
Humans
Idioma:
En
Revista:
Semin Nucl Med
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos