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High frequency of hand foot syndrome with capecitabine.
Kamil, Muhammad; Haron, Mubassir; Yosuff, Narazah; Khalid, Imran; Azman, Nizuwan.
Afiliación
  • Kamil M; Department of Oncology, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia. kamilpk2001@yahoo.com
J Coll Physicians Surg Pak ; 20(6): 421-2, 2010 Jun.
Article en En | MEDLINE | ID: mdl-20642979
A hospital based cross-sectional retrospective study was conducted to determine the frequency of hand foot syndrome (HFS) with Capecitabine as a single agent and in combination with Oxaliplatin. The study included 43 consecutive cases of colorectal carcinoma and conducted from June till December 2008. Patients on palliative care were excluded. SPSS was used for the application of chi-square test, by keeping the level of significance as p < 0.05. Fifteen (34.9%) patients developed HFS, 10 in the single-agent and 5 in the combination group. No significant association of HFS with either regimens was noted (p=0.876).
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Desoxicitidina / Fluorouracilo / Dermatosis del Pie / Dermatosis de la Mano / Antimetabolitos Antineoplásicos Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Coll Physicians Surg Pak Asunto de la revista: MEDICINA Año: 2010 Tipo del documento: Article País de afiliación: Malasia Pais de publicación: Pakistán

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Desoxicitidina / Fluorouracilo / Dermatosis del Pie / Dermatosis de la Mano / Antimetabolitos Antineoplásicos Tipo de estudio: Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Coll Physicians Surg Pak Asunto de la revista: MEDICINA Año: 2010 Tipo del documento: Article País de afiliación: Malasia Pais de publicación: Pakistán