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Plasma thiobarbituric acid reactive substances a predictive marker of cerebral ischemia in patients at high risk?
Alessandri, C; Germani, M; Censi, C; Rudelli, G; Iuliano, L; Servi, M; Ghiselli, A; Violi, F.
Afiliación
  • Alessandri C; Andrea Cesalpino Foundation, La Sapienza University, Rome.
Acta Neurol Scand ; 83(5): 323-7, 1991 May.
Article en En | MEDLINE | ID: mdl-2063655
The clinical meaning of high values of blood lipid peroxides, assessed as thiobarbituric acid reactive substances (TBA-RS), was investigated in 19 selected high risk patients with transient ischemic attacks (TIA). Patients were checked every 3-6 months and followed-up for 3 years. 8 patients experienced further vascular episodes, 4 having minor stroke and 4 TIA; one of the latter died from myocardial infarction. Unlike blood cholesterol and glucose. TBA-RS values discriminated patients with vascular episodes: they, indeed, showed significant higher values of TBA-RS. Discriminant analysis further indicated that TBA-RS levels differentiate patients with and without vascular accidents, suggesting that high blood values of lipid peroxides could represent a predictive sign of vascular ischemia.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiobarbitúricos / Arteriosclerosis Intracraneal / Infarto Cerebral / Ataque Isquémico Transitorio / Peróxidos Lipídicos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Neurol Scand Año: 1991 Tipo del documento: Article Pais de publicación: Dinamarca
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiobarbitúricos / Arteriosclerosis Intracraneal / Infarto Cerebral / Ataque Isquémico Transitorio / Peróxidos Lipídicos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Neurol Scand Año: 1991 Tipo del documento: Article Pais de publicación: Dinamarca