Wavelet-based estimation of the hemodynamic responses in diffuse optical imaging.
Med Image Anal
; 14(4): 606-16, 2010 Aug.
Article
en En
| MEDLINE
| ID: mdl-20494609
Diffuse optical imaging uses light to provide a surrogate measure of neuronal activation through the hemodynamic responses. The relative low absorption of near-infrared light enables measurements of hemoglobin changes at depths reaching the first centimeter of the cortex. The rapid rate of acquisition and the access to both oxy and deoxy-hemoglobin leads to new challenges when trying to uncouple physiology from the signal of interest. In particular, recent work provided evidence of the presence of a 1/f noise structure in optical signals and showed that a general linear model based on wavelets can be used to decorrelate the structured noise and provide a superior estimator of response amplitude when compared with conventional techniques. In this work the wavelet techniques are extended to recover the full temporal shape of the hemodynamic responses. A comparison with other models is provided as well as a case study on finger-tapping data.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Espectrofotometría Infrarroja
/
Encéfalo
/
Mapeo Encefálico
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Corteza Cerebral
/
Circulación Cerebrovascular
/
Potenciales Evocados
/
Análisis de Ondículas
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Med Image Anal
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
Año:
2010
Tipo del documento:
Article
Pais de publicación:
Países Bajos