[ATP-dependent chromatin remodeling complex and its function in regulating chromatin structure].
Yi Chuan
; 32(4): 301-6, 2010 Apr.
Article
en Zh
| MEDLINE
| ID: mdl-20423884
The highly condensed chromatin prevents binding of transcription factors and cofactors to DNA. Therefore, it is crucial to relief the repressive environment for transcription through chromatin remodeling activities. Recently, it is widely accepted that chromatin remodeling is carried out by at least two mechanisms: ATP-dependent chromatin remodeling complex and covalent modifications of histone tails by histone modification complexes. This paper reviews the mechanisms of chromatin remodeling through ATP-dependent chromatin remodeling complex and how the two complexes work together to modify the chromatin structure and regulate the function of transcription mechanism according to recent studies.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cromatina
/
Adenosina Trifosfato
/
Ensamble y Desensamble de Cromatina
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
Zh
Revista:
Yi Chuan
Asunto de la revista:
GENETICA
Año:
2010
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
China