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Efficacy of low-level laser therapy for body contouring and spot fat reduction.
Caruso-Davis, Mary K; Guillot, Thomas S; Podichetty, Vinod K; Mashtalir, Nazar; Dhurandhar, Nikhil V; Dubuisson, Olga; Yu, Ying; Greenway, Frank L.
Afiliación
  • Caruso-Davis MK; School of Human Ecology, Louisiana State University, Baton Rouge, LA 70803, USA.
Obes Surg ; 21(6): 722-9, 2011 Jun.
Article en En | MEDLINE | ID: mdl-20393809
BACKGROUND: Low-level laser therapy (LLLT) is commonly used in medical applications, but scientific studies of its efficacy and the mechanism by which it causes loss of fat from fat cells for body contouring are lacking. This study examined the effectiveness and mechanism by which 635­680 nm LLLT acts as a non-invasive body contouring intervention method. METHODS: Forty healthy men and women ages 18­65 years with a BMI <30 kg/m2 were randomized 1:1 to laser or control treatment. Subject's waistlines were treated 30 min twice a week for 4 weeks. Standardized waist circumference measurements and photographs were taken before and after treatments 1, 3, and 8. Subjects were asked not to change their diet or exercise habits. In vitro assays were conducted to determine cell lysis, glycerol, and triglyceride release. RESULTS: Data were analyzed for those with body weight fluctuations within 1.5 kg during 4 weeks of the study. Each treatment gave a 0.4­0.5 cm loss in waist girth.Cumulative girth loss after 4 weeks was −2.15 cm (−0.78 ± 2.82 vs. 1.35 ± 2.64 cm for the control group,p < 0.05). A blinded evaluation of standardized pictures showed statistically significant cosmetic improvement after 4 weeks of laser treatment. In vitro studies suggested that laser treatment increases fat loss from adipocytes by release of triglycerides, without inducing lipolysis or cell lysis. CONCLUSIONS: LLLT achieved safe and significant girth loss sustained over repeated treatments and cumulative over 4 weeks of eight treatments. The girth loss from the waist gave clinically and statistically significant cosmetic improvement.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Técnicas Cosméticas / Adipocitos / Terapia por Luz de Baja Intensidad / Grasa Subcutánea Abdominal / Sobrepeso / Distribución de la Grasa Corporal / Láseres de Semiconductores Tipo de estudio: Clinical_trials Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Obes Surg Asunto de la revista: METABOLISMO Año: 2011 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Técnicas Cosméticas / Adipocitos / Terapia por Luz de Baja Intensidad / Grasa Subcutánea Abdominal / Sobrepeso / Distribución de la Grasa Corporal / Láseres de Semiconductores Tipo de estudio: Clinical_trials Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Obes Surg Asunto de la revista: METABOLISMO Año: 2011 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos