[Value of diffusion-weighted MR imaging in diagnosis of acute rejection after renal transplantation].
Zhejiang Da Xue Xue Bao Yi Xue Ban
; 39(2): 163-7, 2010 03.
Article
en Zh
| MEDLINE
| ID: mdl-20387244
OBJECTIVE: To evaluate the feasibility of MR diffusion-weighted imaging (DWI) in diagnosis of acute rejection after renal transplantation. METHODS: Sixty-nine patients who underwent renal transplantation were enrolled in the study. According to the clinical features and renal biopsy, 26 patients were designated in rejection group and 43 in non-rejection group. Patients in non-rejection group underwent MR DWI scan at 2 to 3 weeks after operation, and those in rejection group underwent scan at 5 d before or after renal biopsy. Then the apparent diffusion coefficient (ADC) values of transplanted kidneys were measured with high diffusion sensitivity gradient factors (b values). RESULTS: Patients with acute rejection had significantly lower ADC (P <0.04) than non-rejection patients with all the different b values (b=200, 400, 600, 800, 1,000 s/mm(2)). The ROC curves showed that sensitivity and specificity were best when b value was 800 s/mm(2). CONCLUSION: DWI is a potential and reliable non-invasive method for the diagnosis of the acute rejection after renal transplantation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trasplante de Riñón
/
Imagen de Difusión por Resonancia Magnética
/
Rechazo de Injerto
/
Riñón
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
Límite:
Female
/
Humans
/
Male
Idioma:
Zh
Revista:
Zhejiang Da Xue Xue Bao Yi Xue Ban
Asunto de la revista:
MEDICINA
Año:
2010
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
China