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Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilon and DDX3.
Yu, Shiyan; Chen, Jieliang; Wu, Min; Chen, Hui; Kato, Nobuyuki; Yuan, Zhenghong.
Afiliación
  • Yu S; Shanghai Public Health Clinical Center affiliated to Fudan University, Shanghai 201508, PR China.
  • Chen J; Key Laboratory of Medical Molecular Virology, Ministry of Education and Public Health, Shanghai Medical College, Fudan University, Shanghai 200032, PR China.
  • Wu M; Shanghai Public Health Clinical Center affiliated to Fudan University, Shanghai 201508, PR China.
  • Chen H; Key Laboratory of Medical Molecular Virology, Ministry of Education and Public Health, Shanghai Medical College, Fudan University, Shanghai 200032, PR China.
  • Kato N; Shanghai Public Health Clinical Center affiliated to Fudan University, Shanghai 201508, PR China.
  • Yuan Z; Shanghai Public Health Clinical Center affiliated to Fudan University, Shanghai 201508, PR China.
J Gen Virol ; 91(Pt 8): 2080-2090, 2010 Aug.
Article en En | MEDLINE | ID: mdl-20375222
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Productos del Gen pol / Virus de la Hepatitis B / Interferón beta / Factores de Virulencia / Factor 3 Regulador del Interferón / Receptor Toll-Like 3 / ARN Helicasas DEAD-box Límite: Humans Idioma: En Revista: J Gen Virol Año: 2010 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Productos del Gen pol / Virus de la Hepatitis B / Interferón beta / Factores de Virulencia / Factor 3 Regulador del Interferón / Receptor Toll-Like 3 / ARN Helicasas DEAD-box Límite: Humans Idioma: En Revista: J Gen Virol Año: 2010 Tipo del documento: Article Pais de publicación: Reino Unido