State-dependent amygdala stimulation-induced cardiovascular effects in rats.
Chin J Physiol
; 52(6): 432-40, 2009 Dec 31.
Article
en En
| MEDLINE
| ID: mdl-20337151
Stimulation of the amygdala is known to produce pressor, depressor, or has no effects. The present study was performed to test whether amygdala cardiovascular effects are influenced by consciousness states and by different types of anesthetics. Adult rats were set up for stimulation amygdala and measurement of blood pressure in a chronic preparation. After recovery, same sites of the amygdala were stimulated electrically for several trials with the rat under conscious or anesthetic states induced by pentobarbital, urethane, ketamine, alpha-chloralose and urethane plus alpha-chloralose, respectively. The interval between any two stimulation trials was at least 2 days. The stimulation was an 80-Hz, 0.5-ms, 100-micro A square wave pulse train lasting for 15 s. Cardiovascular responsive sites were found in the central, medial, and basolateral nuclei of the amygdala. In stimulating these responsive sites, significantly different cardiovascular effects were induced under a conscious state and an anesthetized state of the animal, yet no significant differences were found among the various anesthetic agents. We conclude, that the cardiovascular influence of the amygdala is state-dependent in the rat.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Inconsciencia
/
Presión Sanguínea
/
Fenómenos Fisiológicos Cardiovasculares
/
Estado de Conciencia
/
Amígdala del Cerebelo
Límite:
Animals
Idioma:
En
Revista:
Chin J Physiol
Año:
2009
Tipo del documento:
Article
Pais de publicación:
India