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An open-source framework of neural networks for diagnosis of coronary artery disease from myocardial perfusion SPECT.
Guner, Levent A; Karabacak, Nese Ilgin; Akdemir, Ozgur U; Karagoz, Pinar Senkul; Kocaman, Sinan A; Cengel, Atiye; Unlu, Mustafa.
Afiliación
  • Guner LA; Department of Nuclear Medicine, Gazi University School of Medicine, Besevler, Ankara, Turkey. leventguner@yahoo.com
J Nucl Cardiol ; 17(3): 405-13, 2010 Jun.
Article en En | MEDLINE | ID: mdl-20204564
BACKGROUND: The purpose of this study is to develop and analyze an open-source artificial intelligence program built on artificial neural networks that can participate in and support the decision making of nuclear medicine physicians in detecting coronary artery disease from myocardial perfusion SPECT (MPS). METHODS AND RESULTS: Two hundred and forty-three patients, who had MPS and coronary angiography within three months, were selected to train neural networks. Six nuclear medicine residents, one experienced nuclear medicine physician, and neural networks evaluated images of 65 patients for presence of coronary artery stenosis. Area under the curve (AUC) of receiver operating characteristics analysis for networks and expert was .74 and .84, respectively. The AUC of the other physicians ranged from .67 to .80. There were no significant differences between expert, neural networks, and standard quantitative values, summed stress score and total stress defect extent. CONCLUSIONS: The open-source neural networks developed in this study may provide a framework for further testing, development, and integration of artificial intelligence into nuclear cardiology environment.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Tomografía Computarizada de Emisión de Fotón Único / Redes Neurales de la Computación / Imagen de Perfusión Miocárdica Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: J Nucl Cardiol Asunto de la revista: CARDIOLOGIA Año: 2010 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Tomografía Computarizada de Emisión de Fotón Único / Redes Neurales de la Computación / Imagen de Perfusión Miocárdica Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Female / Humans / Male / Middle aged Idioma: En Revista: J Nucl Cardiol Asunto de la revista: CARDIOLOGIA Año: 2010 Tipo del documento: Article País de afiliación: Turquía Pais de publicación: Estados Unidos