Presenting exogenous antigen to T cells.
Curr Protoc Immunol
; Chapter 16: 16.2.1-16.2.18, 2010 Feb.
Article
en En
| MEDLINE
| ID: mdl-20143316
Antigen processing and presentation experiments can be done with a wide variety of antigen-presenting cells (APCs). Most experiments will use one of the "professional" APC types: dendritic cells (DCs), macrophages, and B lymphocytes. Other types of cells may be used for antigen presentation in some circumstances. Each type of professional APC has an important antigen-presentation function, but the different APC types contribute to different aspects of the immune response. Therefore, selection of an APC type for study must include consideration of the stage or aspect of immune response that is to be modeled in the experiment. An important technical distinction for some types of experiments is whether the APCs are adherent or nonadherent, since this dictates the procedures that must be used to wash the cells as the medium is changed.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Técnicas Inmunológicas
/
Presentación de Antígeno
/
Técnicas de Cultivo de Célula
/
Células Presentadoras de Antígenos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Protoc Immunol
Año:
2010
Tipo del documento:
Article
Pais de publicación:
Estados Unidos