Genotoxic activity of Eucalyptus globulus essential oil in Aspergillus nidulans diploid cells.
Folia Microbiol (Praha)
; 54(6): 493-8, 2009 Nov.
Article
en En
| MEDLINE
| ID: mdl-20140715
Eucalyptus globulus essential oil was evaluated for its genotoxic potential using a somatic segregation assay and a diploid strain of the fungus Aspergillus nidulans, heterozygous for nutritional and conidia color markers. The main compounds of the current essential oil sample were eucalyptol (49.0 %), alpha-pinene (8.9), beta-pinene (1.5), globulol (6.9), alpha-eudesmol (1.12), spathulenol (1.42), gamma-cadinene (1.45), trans-beta-elemenone (1.23) and aromandendrene (2.3), totaling 74 % of oil. Oil at 0.12 and 0.25 microL/mL was found to increase the mitotic instability of the original diploid strain and the number of diploid mitotic recombinants of A. nidulans. The genotoxicity of the oil was associated with the induction of mitotic crossing-over or with oil-broken chromosomes.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aspergillus nidulans
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ADN de Hongos
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Aceites Volátiles
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Diploidia
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Eucalyptus
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Mutágenos
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Antifúngicos
Idioma:
En
Revista:
Folia Microbiol (Praha)
Año:
2009
Tipo del documento:
Article
Pais de publicación:
Estados Unidos