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[Specificities of chemotherapy in elderly cancer patients]. / Spécificités de la prise en charge par chimiothérapie chez le sujet âgé.
Delbaldo, C; Delbado, C; Caillet, P; Pouessel, D; Paillaud, E; Culine, S.
Afiliación
  • Delbaldo C; Service d'Oncologie Médicale, Unité d'Onco-gériatrie, CHU Henri Mondor, Université Paris 12, Paris, France.
Prog Urol ; 19 Suppl 3: S100-5, 2009 Nov.
Article en Fr | MEDLINE | ID: mdl-20123491
The management of cancer in the elderly patients is becoming a major problem of public health. The population is becoming older, the risk of cancer is increasing with age and therapeutic tools are improving. The numerous pharmacological changes of age might influence the pharmacokinetic and pharmacodynamic variables of many drugs, in particular the agents of chemotherapy. The development of news drugs, with less toxicity, administrated weekly or orally, and of supportive care (hematological growth factors, nutritional support) allows proposing specific treatment to elderly patients with cancer. However, evidence-based medicine data are lacking to define optimal schedules in this population due to low inclusion rates in clinical trials. This paper explores the specificities of chemotherapy in elderly patients with cancer.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Urológicas Límite: Aged / Humans Idioma: Fr Revista: Prog Urol Asunto de la revista: UROLOGIA Año: 2009 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Francia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Urológicas Límite: Aged / Humans Idioma: Fr Revista: Prog Urol Asunto de la revista: UROLOGIA Año: 2009 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Francia