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Correlates of adherence to respiratory drugs in COPD patients.
Laforest, Laurent; Denis, Francois; Van Ganse, Eric; Ritleng, Cecile; Saussier, Christel; Passante, Nadine; Devouassoux, Gilles; Chatté, Gerard; Freymond, Nathalie; Pacheco, Yves.
Afiliación
  • Laforest L; Unité de Neuro-Pharmaco-Epidémiologie, CHU: University Hospital Lyon, Lyon, France.
Prim Care Respir J ; 19(2): 148-54, 2010 Jun.
Article en En | MEDLINE | ID: mdl-20094689
AIMS: To identify the correlates of accidental omissions and intentional interruptions of respiratory therapy in COPD. METHODS: COPD patients (GOLD stages II-IV) were recruited by general practitioners or respiratory physicians. Patients reported in self-report questionnaires their adherence to respiratory drugs (over the past three months) and their perception of therapy. RESULTS: 179 patients were included (mean age 63 years, 24% females). 45% forgot their respiratory therapy, while 30% interrupted it in the absence of any perceived benefit. The risks of accidental omissions were significantly higher when patients complained about having too many medications to take on a daily basis (OR=2.35; 95%CI=1.13-4.89), and among current smokers (OR=2.14; 95%CI=1.07-4.29). Females were more likely to interrupt therapy intentionally (OR=2.40; 95%CI=1.04-5.53). Surprisingly, there was no significant relationship with the number of drugs actually taken by patients. CONCLUSIONS: Adherence to respiratory drugs is inadequate in COPD patients. In order to improve adherence, patients' perception of the burden of therapy should not be overlooked.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fármacos del Sistema Respiratorio / Enfermedad Pulmonar Obstructiva Crónica / Cumplimiento de la Medicación Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Prim Care Respir J Año: 2010 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fármacos del Sistema Respiratorio / Enfermedad Pulmonar Obstructiva Crónica / Cumplimiento de la Medicación Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Prim Care Respir J Año: 2010 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido