Your browser doesn't support javascript.
loading
In vitro postantibiotic effects of tomopenem (CS-023) against Staphylococcus aureus and Pseudomonas aeruginosa.
Tomozawa, Takanori; Sugihara, Chika; Kakuta, Masayo; Sugihara, Kiyoshi; Koga, Tetsufumi.
Afiliación
  • Tomozawa T; Biological Research Laboratories IV, Daiichi Sankyo Co. Ltd, 1-2-58 Hiromachi,Shinagawa-ku, Tokyo 140-8710, Japan.
  • Sugihara C; Biological Research Laboratories IV, Daiichi Sankyo Co. Ltd, 1-2-58 Hiromachi,Shinagawa-ku, Tokyo 140-8710, Japan.
  • Kakuta M; Biological Research Laboratories IV, Daiichi Sankyo Co. Ltd, 1-2-58 Hiromachi,Shinagawa-ku, Tokyo 140-8710, Japan.
  • Sugihara K; Biological Research Laboratories IV, Daiichi Sankyo Co. Ltd, 1-2-58 Hiromachi,Shinagawa-ku, Tokyo 140-8710, Japan.
  • Koga T; Biological Research Laboratories IV, Daiichi Sankyo Co. Ltd, 1-2-58 Hiromachi,Shinagawa-ku, Tokyo 140-8710, Japan.
J Med Microbiol ; 59(Pt 4): 438-441, 2010 Apr.
Article en En | MEDLINE | ID: mdl-20093378
The postantibiotic effect (PAE) of tomopenem was determined after a 2 h exposure of two strains of meticillin-susceptible and meticillin-resistant Staphylococcus aureus (MSSA and MRSA), and imipenem-susceptible and imipenem-resistant Pseudomonas aeruginosa, to tenfold the respective MIC. The PAEs on MSSA and P. aeruginosa were approximately 1 h and they were comparable to those of meropenem. The PAE on MRSA was 1.5 to 3 h, equal to or longer than those of vancomycin. The PAEs of tomopenem not only were found for MRSA, but also were present in the imipenem-resistant P. aeruginosa tested.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pseudomonas aeruginosa / Staphylococcus aureus / Carbapenémicos / Antibacterianos Idioma: En Revista: J Med Microbiol Año: 2010 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pseudomonas aeruginosa / Staphylococcus aureus / Carbapenémicos / Antibacterianos Idioma: En Revista: J Med Microbiol Año: 2010 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido