[Autologous mesenchymal stem cells culture from adipose tissue for treatment of facial rhytids]. / Cultura autóloga de células-tronco mesenquimais de tecido adiposo para o tratamento de rítides faciais.
Rev Col Bras Cir
; 36(4): 288-91, 2009 Aug.
Article
en Pt
| MEDLINE
| ID: mdl-20076916
OBJECTIVE: To test the effect of mesenchymal stem cells (MSC) from adipose tissue on the dermal filling for nasolabial rhytids correction. METHODS: 50 cc of infraumbilical fat and 20 ml of peripheral blood were harvested to isolate MSC and autologous plasma from 15 female volunteers, respectively. The volunteers were grouped in according to the following strategies of intra-dermal injection: Group (I) only hyaluronic acid; Group (II) only MSC; Group (III) MSC combined with hyaluronic acid. For this qualitative and prospective study photographic monitoring was done monthly. RESULTS: In the group (I) we observed an immediate effect of filling; in the group (II) the effect of filling was reached after approximately two months. In the group (III) filling occurred more efficiently and progressively, probably due to the combination of the short and long-term effects generated by the hyaluronic acid and MSC, respectively. CONCLUSION: MSC when combined with hyaluronic acid were able to fill in deep folds, with progressive improvement of skin tone and decreasing lines of expression.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ritidoplastia
/
Tejido Adiposo
/
Trasplante de Células Madre Mesenquimatosas
Tipo de estudio:
Observational_studies
/
Qualitative_research
Límite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
Pt
Revista:
Rev Col Bras Cir
Año:
2009
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Brasil