The biocompatability of mesoporous inorganic-organic hybrid resin films with ionic and hydrophilic characteristics.
Biomaterials
; 31(9): 2517-25, 2010 Mar.
Article
en En
| MEDLINE
| ID: mdl-20045180
New mesoporous silicate-titania resin systems hybridized with 4,5-dihydroxy-m-benzenedisulfonic acid and poly(ethylene glycol)-dimethacrylate component were developed. These inorganic-organic hybrid resins were found to reveal highly controlled ionic and hydrophilic surface with excellent durability and adhesion onto various substrates. The resin films revealed high resistance to nonspecific adsorption of fibrinogen and to adherence by several bacterial pathogens such as Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis and Enterococcus faecalis. Furthermore, excellent biocompatibility of the developed resins was proved by both HEp-2 cell adhesion in vitro and subcutaneous implantation in mice. The inorganic-organic hybrid resins are strongly promising for biomedical applications including biomedical devices and biosensors.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polietilenglicoles
/
Resinas Sintéticas
/
Bencenosulfonatos
/
Materiales Biocompatibles
/
Ensayo de Materiales
/
Metacrilatos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Biomaterials
Año:
2010
Tipo del documento:
Article
Pais de publicación:
Países Bajos